Selected Research Articles in recent 5 years
Qiu, S.#, Liu, L.#, Xiang, B.#, Jin, Z., Li, Y., Li, D., Hou, H., Li, K., Wei, G., Xie, J., Li, S., Liu, S., Chen, C., Liang, X., Sun, Q. and Xiong, W. (2026). Template-independent genome editing and restoration for correcting frameshift disorders. Nat Biomed Eng DOI: 10.1038/s41551-026-01635-5.
Wei, G.#, S. Qiu#, X. Gao#, L. Zheng, Y. Chen, Y. Ma, H. Feng, J. Yang, G. Dong, H. Nie, W. Zhao, X. Li, G. Wang, W. Xiong*, P. Dai*, and Y. Yuan*. (2025) Single Administration of AAV-mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2-Induced Lysosomal Dysfunction in Hair Cells, Adv Sci (Weinh): e2408878 DOI: 10.1002/advs.202408878.
Li, N.#, Liu, S.#, Zhao, D.#, Du, H., Xi, Y., Wei, X., Liu, Q., Müller, U., Lu, Q.*, Xiong, W.*, Xu, Z.* (2024) Disruption of Cdh23 exon 68 splicing leads to progressive hearing loss in mouse through affecting tip-link stability. Proc Natl Acad Sci U S A 121, e2309656121 DOI: 10.1073/pnas.2309656121.
Wang, X.#, Liu, S.#, Cheng, Q., Qu, C., Ren, R., Du, H., Li, N., Yan, K., Wang, Y., Xiong, W.*, and Xu, Z.* (2023) CIB2 and CIB3 Regulate Stereocilia Maintenance and Mechanoelectrical Transduction in Mouse Vestibular Hair Cells. J Neurosci 43, 3219-3231 DOI: 10.1523/JNEUROSCI.1807-22.2023.
Liu, L.#, Zou, L.#, Li, K.#, Hou, H., Hu, Q., Liu, S., Li, J., Song, C., Chen, J., Wang, S., Wang, Y., Li, C., Du, H., Li, J. L., Chen, F., Xu, Z., Sun, W., Sun, Q., and Xiong, W. (2022) Template-independent genome editing in the Pcdh15(av-3j) mouse, a model of human DFNB23 nonsyndromic deafness. Cell Rep 40(2), 111061 DOI: 10.1016/j.celrep.2022.111061.
Li, J.#, Liu, S.#, Song, C.#, Zhu, T., Zhao, Z., Sun, W., Wang, Y.*, Song, L.*, and Xiong, W.* (2022) Prestin-Mediated Frequency Selectivity Does not Cover Ultrahigh Frequencies in Mice. Neuroscience Bulletin 38(7): 769-784 DOI: 10.1007/s12264-022-00839-4.
Yan, Y.#, Tian, M.#, Li, M., Zhou, G., Chen, Q., Xu, M., Hu, Y., Luo, W., Guo, X., Zhang, C., Xie, H., Wu, Q. F., Xiong, W.*, Liu, S.*, and Guan, J. S.* (2022) ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder. Neuron 6273 (21) 01090-4 DOI: 10.1016/j.neuron.2021.12.035.
Zhang, Y.#, Lin, G.#, Wang, Y.#*, Xue, N., Lin, X., Du, T.*, Xiong, W.*, and Song, L.* (2021) Prestin derived OHC surface area reduction underlies age-related rescaling of frequency place coding. Hearing Research 108406 DOI: 10.1016/j.heares.2021.108406.
Song, C.#, Li, J.#, Liu, S., Hou, H., Zhu, T., Chen, J., Liu, L., Jia, Y., and Xiong, W. (2021) An L1 retrotransposon insertion induced deafness mouse model for studying the development and function of the cochlear stria vascularis. Proc Natl Acad Sci U S A 118 (40) e2107933118 DOI: 10.1073/pnas.2107933118.
Li, J.#, Liu, S.#, Song, C.#, Hu, Q.#, Zhao, Z.#, Deng, T., Wang, Y., Zhu, T., Zou, L., Wang, S., Chen, J., Liu, L., Hou, H., Yuan, K., Zheng, H., Liu, Z., Chen, X., Sun, W., Xiao, B., and Xiong, W. (2021) PIEZO2 mediates ultrasonic hearing via cochlear outer hair cells in mice. Proc Natl Acad Sci U S A 118 (28) e2101207118 DOI: 10.1073/pnas.2101207118.
Reviews and Book Chapters
Liu, S., Wang, S., Zou, L., and Xiong, W. (2021) Mechanisms in cochlear hair cell mechano-electrical transduction for acquisition of sound frequency and intensity. Cell Mol Life Sci 78, 5083-5094. (Review)
Xiong, W. and Xu, Z. (2018) Mechanotransduction of the Hair Cell. Springer Singapore. (Book)
